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Cardiac dysfunction in adipose triglyceride lipase deficiency: treatment with a PPARα agonist
BACKGROUND AND PURPOSE: Adipose triglyceride lipase (ATGL) has been identified as a rate-limiting enzyme of mammalian triglyceride catabolism. Deletion of the ATGL gene in mice results in severe lipid accumulation in a variety of tissues including the heart. In the present study we investigated card...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268192/ https://www.ncbi.nlm.nih.gov/pubmed/21585347 http://dx.doi.org/10.1111/j.1476-5381.2011.01490.x |