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NOP Receptor Ligands as Potential Agents for Inflammatory and Autoimmune Diseases
Nociceptin/orphanin FQ (N/OFQ) is a seventeen-amino acid peptide that is the endogenous ligand of a G-protein-coupled receptor (NOP). Various immune cells express the precursor protein and secrete N/OFQ as well as display binding sites for this peptide. The functional capacity of NOP receptor was de...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE-Hindawi Access to Research
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268226/ https://www.ncbi.nlm.nih.gov/pubmed/22312472 http://dx.doi.org/10.4061/2011/836569 |