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NOP Receptor Ligands as Potential Agents for Inflammatory and Autoimmune Diseases

Nociceptin/orphanin FQ (N/OFQ) is a seventeen-amino acid peptide that is the endogenous ligand of a G-protein-coupled receptor (NOP). Various immune cells express the precursor protein and secrete N/OFQ as well as display binding sites for this peptide. The functional capacity of NOP receptor was de...

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Detalles Bibliográficos
Autores principales: Gavioli, Elaine C., Romão, Pedro R. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268226/
https://www.ncbi.nlm.nih.gov/pubmed/22312472
http://dx.doi.org/10.4061/2011/836569