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Glucagon-like peptide-1 receptor activation reduces ischaemic brain damage following stroke in Type 2 diabetic rats

Diabetes is a strong risk factor for premature and severe stroke. The GLP-1R (glucagon-like peptide-1 receptor) agonist Ex-4 (exendin-4) is a drug for the treatment of T2D (Type 2 diabetes) that may also have neuroprotective effects. The aim of the present study was to determine the efficacy of Ex-4...

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Detalles Bibliográficos
Autores principales: Darsalia, Vladimer, Mansouri, Shiva, Ortsäter, Henrik, Olverling, Anna, Nozadze, Nino, Kappe, Camilla, Iverfeldt, Kerstin, Tracy, Linda M., Grankvist, Nina, Sjöholm, Åke, Patrone, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268352/
https://www.ncbi.nlm.nih.gov/pubmed/22150224
http://dx.doi.org/10.1042/CS20110374