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A water soluble tri-cationic porphyrin–EDTA conjugate induces apoptosis in human neuroendocrine tumor cell lines

In this study, a completely water soluble tri-cationic porphyrin–EDTA conjugate was synthesized. We present data demonstrating the tumoristatic effects of the novel fully water soluble cationic porphyrin TMPy(3)PhenEDTA-P-Cl(4) in the dark, in the medullary thyroid carcinoma cell lines MTC-SK and SH...

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Detalles Bibliográficos
Autores principales: Schwach, Gert, Thamyongkit, Patchanita, Reith, Lorenz Michael, Svejda, Bernhard, Knör, Günther, Pfragner, Roswitha, Schoefberger, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268353/
https://www.ncbi.nlm.nih.gov/pubmed/22024042
http://dx.doi.org/10.1016/j.bioorg.2011.09.006