Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl-4(1H)-quinolones

A series of 23 new 1-methyl-2-alkenyl-4(1H)quinolones have been synthesized and evaluated in vitro for their antimycobacterial activities against fast growing species of mycobacteria, such as Mycobacterium fortuitum, M. smegmatis and M. phlei. The compounds displayed good to excellent inhibition of...

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Detalles Bibliográficos
Autores principales: Wube, Abraham A., Hüfner, Antje, Thomaschitz, Christina, Blunder, Martina, Kollroser, Manfred, Bauer, Rudolf, Bucar, Franz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268452/
https://www.ncbi.nlm.nih.gov/pubmed/21106378
http://dx.doi.org/10.1016/j.bmc.2010.10.060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268452/
https://www.ncbi.nlm.nih.gov/pubmed/21106378
http://dx.doi.org/10.1016/j.bmc.2010.10.060

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