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Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl-4(1H)-quinolones
A series of 23 new 1-methyl-2-alkenyl-4(1H)quinolones have been synthesized and evaluated in vitro for their antimycobacterial activities against fast growing species of mycobacteria, such as Mycobacterium fortuitum, M. smegmatis and M. phlei. The compounds displayed good to excellent inhibition of...
Autores principales: | Wube, Abraham A., Hüfner, Antje, Thomaschitz, Christina, Blunder, Martina, Kollroser, Manfred, Bauer, Rudolf, Bucar, Franz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268452/ https://www.ncbi.nlm.nih.gov/pubmed/21106378 http://dx.doi.org/10.1016/j.bmc.2010.10.060 |
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