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Dark Matter: Are Mice the Solution to Missing Heritability?

Genome-wide association studies (GWAS) in humans have identified hundreds of single nucleotide polymorphisms associated with complex traits, yet for most traits studied, the sum total of all these identified variants fail to explain a significant portion of the heritable variation. Reasons for this...

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Detalles Bibliográficos
Autores principales: Parker, Clarissa C., Palmer, Abraham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268586/
https://www.ncbi.nlm.nih.gov/pubmed/22303328
http://dx.doi.org/10.3389/fgene.2011.00032