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Mthfs is an Essential Gene in Mice and a Component of the Purinosome

Tetrahydrofolates (THF) are a family of cofactors that function as one-carbon donors in folate-dependent one-carbon metabolism, a metabolic network required for the de novo synthesis of purines, thymidylate, and for the remethylation of homocysteine to methionine in the cytoplasm. 5-FormylTHF is not...

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Detalles Bibliográficos
Autores principales: Field, Martha S., Anderson, Donald D., Stover, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268590/
https://www.ncbi.nlm.nih.gov/pubmed/22303332
http://dx.doi.org/10.3389/fgene.2011.00036