Estimating Allele Frequency from Next-Generation Sequencing of Pooled Mitochondrial DNA Samples

Background: Both common and rare mitochondrial DNA (mtDNA) variants may contribute to genetic susceptibility to some complex human diseases. Understanding of the role of mtDNA variants will provide valuable insights into the etiology of these diseases. However, to date, there have not been any large...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Tao, Pradhan, Kith, Ye, Kenny, Wong, Lee-Jun, Rohan, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268604/
https://www.ncbi.nlm.nih.gov/pubmed/22303347
http://dx.doi.org/10.3389/fgene.2011.00051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268604/
https://www.ncbi.nlm.nih.gov/pubmed/22303347
http://dx.doi.org/10.3389/fgene.2011.00051

Ejemplares similares