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Hybrid Modeling of Cell Signaling and Transcriptional Reprogramming and Its Application in C. elegans Development

Modeling of signal driven transcriptional reprogramming is critical for understanding of organism development, human disease, and cell biology. Many current modeling techniques discount key features of the biological sub-systems when modeling multiscale, organism-level processes. We present a mechan...

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Detalles Bibliográficos
Autores principales: Fertig, Elana J., Danilova, Ludmila V., Favorov, Alexander V., Ochs, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268630/
https://www.ncbi.nlm.nih.gov/pubmed/22303372
http://dx.doi.org/10.3389/fgene.2011.00077