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Hybrid Modeling of Cell Signaling and Transcriptional Reprogramming and Its Application in C. elegans Development
Modeling of signal driven transcriptional reprogramming is critical for understanding of organism development, human disease, and cell biology. Many current modeling techniques discount key features of the biological sub-systems when modeling multiscale, organism-level processes. We present a mechan...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268630/ https://www.ncbi.nlm.nih.gov/pubmed/22303372 http://dx.doi.org/10.3389/fgene.2011.00077 |