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Trans-splicing in Higher Eukaryotes: Implications for Cancer Development?

Trans-splicing, the possibility of exons from distinct pre-mRNAs to join together, is still a concept in gene expression that is generally regarded of limited significance. However, recent work has provided evidence that in human tumors trans-splicing events may precede chromosomal rearrangements. I...

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Detalles Bibliográficos
Autor principal: Zaphiropoulos, Peter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268641/
https://www.ncbi.nlm.nih.gov/pubmed/22303386
http://dx.doi.org/10.3389/fgene.2011.00092