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Trans-splicing in Higher Eukaryotes: Implications for Cancer Development?
Trans-splicing, the possibility of exons from distinct pre-mRNAs to join together, is still a concept in gene expression that is generally regarded of limited significance. However, recent work has provided evidence that in human tumors trans-splicing events may precede chromosomal rearrangements. I...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Research Foundation
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268641/ https://www.ncbi.nlm.nih.gov/pubmed/22303386 http://dx.doi.org/10.3389/fgene.2011.00092 |