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A Network of Regulations by Small Non-Coding RNAs: The P-TEFb Kinase in Development and Pathology

Part of the heterodimeric P-TEF-b element of the Pol II transcription machinery, the cyclin-dependent kinase 9 plays a critical role in gene expression. Phosphorylation of several residues in the polymerase is required for elongation of transcript. It determines the rates of transcription and thus,...

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Detalles Bibliográficos
Autores principales: Ghanbarian, Hossein, Grandjean, Valérie, Cuzin, François, Rassoulzadegan, Minoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268644/
https://www.ncbi.nlm.nih.gov/pubmed/22303389
http://dx.doi.org/10.3389/fgene.2011.00095