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Localization and retention of p90 ribosomal S6 kinase 1 in the nucleus: implications for its function

Ribosomal S6 kinase 1 (RSK1) belongs to a family of proteins with two kinase domains. Following activation in the cytoplasm by extracellular signal-regulated kinases (ERK1/2), it mediates the cell-proliferative, cell-growth, and survival-promoting actions of a number of growth factors and other agon...

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Detalles Bibliográficos
Autores principales: Gao, Xianlong, Chaturvedi, Deepti, Patel, Tarun B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268728/
https://www.ncbi.nlm.nih.gov/pubmed/22130794
http://dx.doi.org/10.1091/mbc.E11-07-0658