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A study of Smad4, Smad6 and Smad7 in Surgically Resected Samples of Pancreatic Ductal Adenocarcinoma and Their Correlation with Clinicopathological Parameters and Patient Survival

BACKGROUND: Smad4 is the common mediator of the tumor suppressive functions of TGF-beta. Smad6 and Smad7 are the antagonists of the TGF-beta pathway. This study investigates the differential protein expressions of Smad4, Smad6 and Smad7 in tumor as compared to normal tissue of pancreatic ductal aden...

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Detalles Bibliográficos
Autores principales: Singh, Puneet, Srinivasan, Radhika, Wig, Jai Dev, Radotra, Bishan Das
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268768/
https://www.ncbi.nlm.nih.gov/pubmed/22195733
http://dx.doi.org/10.1186/1756-0500-4-560