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Region-specific deletions of RIM1 reproduce a subset of global RIM1α(−/−) phenotypes

The presynaptic protein RIM1α mediates multiple forms of presynaptic plasticity at both excitatory and inhibitory synapses. Previous studies of mice lacking RIM1α (RIM1α(−/−) throughout the brain showed that deletion of RIM1α results in multiple behavioral abnormalities. In an effort to begin to del...

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Detalles Bibliográficos
Autores principales: Haws, M E, Kaeser, P S, Jarvis, D L, Südhof, T C, Powell, C M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268893/
https://www.ncbi.nlm.nih.gov/pubmed/22103334
http://dx.doi.org/10.1111/j.1601-183X.2011.00755.x