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IRX-2, a novel biologic, favors the expansion of T effector over T regulatory cells in a human tumor microenvironment model
IRX-2, a natural cytokine biological with multiple components, has been used in preclinical and clinical studies to promote antitumor activity of T lymphocytes. To define cellular mechanisms responsible for antitumor effects of IRX-2, its ability to induce effector T cells (Teff) was examined in a m...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268969/ https://www.ncbi.nlm.nih.gov/pubmed/21915712 http://dx.doi.org/10.1007/s00109-011-0813-8 |