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BMP-7 inhibits TGF-β-induced invasion of breast cancer cells through inhibition of integrin β(3) expression

BACKGROUND: The transforming growth factor (TGF)-β superfamily comprises cytokines such as TGF-β and Bone Morphogenetic Proteins (BMPs), which have a critical role in a multitude of biological processes. In breast cancer, high levels of TGF-β are associated with poor outcome, whereas inhibition of T...

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Detalles Bibliográficos
Autores principales: Naber, Hildegonda P. H., Wiercinska, Eliza, Pardali, Evangelia, van Laar, Theo, Nirmala, Ella, Sundqvist, Anders, van Dam, Hans, van der Horst, Geertje, van der Pluijm, Gabri, Heckmann, Bertrand, Danen, Erik H. J., ten Dijke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268977/
https://www.ncbi.nlm.nih.gov/pubmed/21935711
http://dx.doi.org/10.1007/s13402-011-0058-0