Pharmacokinetics of memantine in rats and mice

To evaluate the potential of memantine as a therapeutic agent for Huntington’s disease (HD) we have undertaken a series of in vitro, ex vivo and whole animal studies to characterize its pharmacokinetics (PK) and pharmacodynamics (PD) in rats and mice. Results from these studies will enable determina...

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Detalles Bibliográficos
Autores principales: Beconi, Maria G., Howland, David, Park, Larry, Lyons, Kathryn, Giuliano, Joseph, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Pacifici, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Huntington Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269340/
https://www.ncbi.nlm.nih.gov/pubmed/22307216
http://dx.doi.org/10.1371/currents.RRN1291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269340/
https://www.ncbi.nlm.nih.gov/pubmed/22307216
http://dx.doi.org/10.1371/currents.RRN1291

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