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Hyperglycemia raises the threshold of levosimendan- but not milrinone-induced postconditioning in rat hearts

BACKGROUND: The authors examined whether milrinone and levosimendan could exert cardiac postconditioning effects in rats under normoglycemia and hyperglycemia, and whether the effects could be mediated by mitochondrial permeability transition pore (mPTP). METHODS: Wistar rats underwent 30-min corona...

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Detalles Bibliográficos
Autores principales: Matsumoto, Shuhei, Cho, Sungsam, Tosaka, Shinya, Higashijima, Ushio, Maekawa, Takuji, Hara, Tetsuya, Sumikawa, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269349/
https://www.ncbi.nlm.nih.gov/pubmed/22239823
http://dx.doi.org/10.1186/1475-2840-11-4