Lymphoid enhancer-binding factor 1, a representative of vertebrate-specific Lef1/Tcf1 sub-family, is a Wnt-beta-catenin pathway target gene in human endothelial cells which regulates matrix metalloproteinase-2 expression and promotes endothelial cell invasion

BACKGROUND: Wnt signaling is activated in many types of cancer and normal physiological processes. Various Wnt-related secreted factors may influence angiogenesis both in the tumor microenvironment and in normal tissues by direct action on endothelial cells. The mechanism of this Wnt action in angio...

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Detalles Bibliográficos
Autores principales: Planutiene, Marina, Planutis, Kestutis, Holcombe, Randall F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269378/
https://www.ncbi.nlm.nih.gov/pubmed/22168911
http://dx.doi.org/10.1186/2045-824X-3-28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269378/
https://www.ncbi.nlm.nih.gov/pubmed/22168911
http://dx.doi.org/10.1186/2045-824X-3-28

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