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Measurement of Hepatic Protein Fractional Synthetic Rate with Stable Isotope Labeling Technique in Thapsigargin Stressed HepG2 Cells

Severe burn-induced liver damage and dysfunction is associated with endoplasmic reticulum (ER) stress. ER stress has been shown to regulate global protein synthesis. In the current study, we induced ER stress in vitro and estimated the effect of ER stress on hepatic protein synthesis. The aim was tw...

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Detalles Bibliográficos
Autores principales: Song, Juquan, Zhang, Xiao-jun, Boehning, Darren, Brooks, Natasha C., Herndon, David N., Jeschke, Marc G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269609/
https://www.ncbi.nlm.nih.gov/pubmed/22298954
http://dx.doi.org/10.7150/ijbs.3660