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Lewis y Regulate Cell Cycle Related Factors in Ovarian Carcinoma Cell RMG-I in Vitro via ERK and Akt Signaling Pathways

OBJECTIVE: To investigate the effect of Lewis y overexpression on the expression of proliferation-related factors in ovarian cancer cells. METHODS: mRNA levels of cyclins, CDKs, and CKIs were measured in cells before and after transfection with the α1,2-fucosyltransferase gene by real-time PCR, and...

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Detalles Bibliográficos
Autores principales: Liu, Dawo, Liu, Juanjuan, Lin, Bei, Liu, Shuice, Hou, Rui, Hao, Yingying, Liu, Qing, Zhang, Shulan, Iwamori, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269723/
https://www.ncbi.nlm.nih.gov/pubmed/22312289
http://dx.doi.org/10.3390/ijms13010828