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Binary fluorous tagging enables the synthesis and separation of a sixteen-stereoisomer library of macrosphelides
Fluorous mixture synthesis minimizes the effort to synthesize small molecule libraries by labeling the molecules rather than the reaction vessels. Reactants are labeled with fluorinated tags and products can later be demixed based on fluorine content. A limit in the number of available tags can be o...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269761/ https://www.ncbi.nlm.nih.gov/pubmed/22270645 http://dx.doi.org/10.1038/nchem.1233 |