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Identification of novel targets for breast cancer by exploring gene switches on a genome scale

BACKGROUND: An important feature that emerges from analyzing gene regulatory networks is the "switch-like behavior" or "bistability", a dynamic feature of a particular gene to preferentially toggle between two steady-states. The state of gene switches plays pivotal roles in cell...

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Detalles Bibliográficos
Autores principales: Wu, Ming, Liu, Li, Chan, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269833/
https://www.ncbi.nlm.nih.gov/pubmed/22053771
http://dx.doi.org/10.1186/1471-2164-12-547