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Asc Modulates the Function of NLRC4 in Response to Infection of Macrophages by Legionella pneumophila
Nucleotide-binding domain, leucine-rich repeat containing proteins (NLRs) activate caspase-1 in response to a variety of bacterium-derived signals in macrophages. NLR-mediated activation of caspase-1 by Legionella pneumophila occurs through both an NLRC4/NAIP5-dependent pathway and a pathway requiri...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Society of Microbiology
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269931/ https://www.ncbi.nlm.nih.gov/pubmed/21771913 http://dx.doi.org/10.1128/mBio.00117-11 |