Predicting Target DNA Sequences of DNA-Binding Proteins Based on Unbound Structures

DNA-binding proteins such as transcription factors use DNA-binding domains (DBDs) to bind to specific sequences in the genome to initiate many important biological functions. Accurate prediction of such target sequences, often represented by position weight matrices (PWMs), is an important step to u...

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Detalles Bibliográficos
Autores principales: Chen, Chien-Yu, Chien, Ting-Ying, Lin, Chih-Kang, Lin, Chih-Wei, Weng, Yi-Zhong, Chang, Darby Tien-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270014/
https://www.ncbi.nlm.nih.gov/pubmed/22312425
http://dx.doi.org/10.1371/journal.pone.0030446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270014/
https://www.ncbi.nlm.nih.gov/pubmed/22312425
http://dx.doi.org/10.1371/journal.pone.0030446

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