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Predicting Target DNA Sequences of DNA-Binding Proteins Based on Unbound Structures
DNA-binding proteins such as transcription factors use DNA-binding domains (DBDs) to bind to specific sequences in the genome to initiate many important biological functions. Accurate prediction of such target sequences, often represented by position weight matrices (PWMs), is an important step to u...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270014/ https://www.ncbi.nlm.nih.gov/pubmed/22312425 http://dx.doi.org/10.1371/journal.pone.0030446 |