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Evolutionary and functional insights into Leishmania META1: evidence for lateral gene transfer and a role for META1 in secretion

BACKGROUND: Leishmania META1 has for long been a candidate molecule for involvement in virulence: META1 transcript and protein are up-regulated in metacyclic Leishmania. Yet, how META1 contributes to virulence remains unclear. We sought insights into the possible functions of META1 by studying its e...

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Detalles Bibliográficos
Autores principales: Puri, Vidhi, Goyal, Aneesh, Sankaranarayanan, Rajan, Enright, Anton J, Vaidya, Tushar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270026/
https://www.ncbi.nlm.nih.gov/pubmed/22093578
http://dx.doi.org/10.1186/1471-2148-11-334