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Evolutionary and functional insights into Leishmania META1: evidence for lateral gene transfer and a role for META1 in secretion
BACKGROUND: Leishmania META1 has for long been a candidate molecule for involvement in virulence: META1 transcript and protein are up-regulated in metacyclic Leishmania. Yet, how META1 contributes to virulence remains unclear. We sought insights into the possible functions of META1 by studying its e...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270026/ https://www.ncbi.nlm.nih.gov/pubmed/22093578 http://dx.doi.org/10.1186/1471-2148-11-334 |