Polyglutamine Repeats Are Associated to Specific Sequence Biases That Are Conserved among Eukaryotes

Nine human neurodegenerative diseases, including Huntington's disease and several spinocerebellar ataxia, are associated to the aggregation of proteins comprising an extended tract of consecutive glutamine residues (polyQs) once it exceeds a certain length threshold. This event is believed to b...

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Detalles Bibliográficos
Autores principales: Ramazzotti, Matteo, Monsellier, Elodie, Kamoun, Choumouss, Degl'Innocenti, Donatella, Melki, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270027/
https://www.ncbi.nlm.nih.gov/pubmed/22312432
http://dx.doi.org/10.1371/journal.pone.0030824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270027/
https://www.ncbi.nlm.nih.gov/pubmed/22312432
http://dx.doi.org/10.1371/journal.pone.0030824

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