Trans-Synaptic Spread of Tau Pathology In Vivo

Tauopathy in the brain of patients with Alzheimer's disease starts in the entorhinal cortex (EC) and spreads anatomically in a defined pattern. To test whether pathology initiating in the EC spreads through the brain along synaptically connected circuits, we have generated a transgenic mouse mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Li, Drouet, Valerie, Wu, Jessica W., Witter, Menno P., Small, Scott A., Clelland, Catherine, Duff, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270029/
https://www.ncbi.nlm.nih.gov/pubmed/22312444
http://dx.doi.org/10.1371/journal.pone.0031302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270029/
https://www.ncbi.nlm.nih.gov/pubmed/22312444
http://dx.doi.org/10.1371/journal.pone.0031302

Ejemplares similares