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Trans-Synaptic Spread of Tau Pathology In Vivo

Tauopathy in the brain of patients with Alzheimer's disease starts in the entorhinal cortex (EC) and spreads anatomically in a defined pattern. To test whether pathology initiating in the EC spreads through the brain along synaptically connected circuits, we have generated a transgenic mouse mo...

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Detalles Bibliográficos
Autores principales:	Liu, Li, Drouet, Valerie, Wu, Jessica W., Witter, Menno P., Small, Scott A., Clelland, Catherine, Duff, Karen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270029/ https://www.ncbi.nlm.nih.gov/pubmed/22312444 http://dx.doi.org/10.1371/journal.pone.0031302

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