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Genetic Association Analysis Using Sibship Data: A Multilevel Model Approach

Family based association study (FBAS) has the advantages of controlling for population stratification and testing for linkage and association simultaneously. We propose a retrospective multilevel model (rMLM) approach to analyze sibship data by using genotypic information as the dependent variable....

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Detalles Bibliográficos
Autores principales: Zhao, Yang, Yu, Hao, Zhu, Ying, Ter-Minassian, Monica, Peng, Zhihang, Shen, Hongbing, Diao, Nancy, Chen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270036/
https://www.ncbi.nlm.nih.gov/pubmed/22312441
http://dx.doi.org/10.1371/journal.pone.0031134