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Genetic Association Analysis Using Sibship Data: A Multilevel Model Approach
Family based association study (FBAS) has the advantages of controlling for population stratification and testing for linkage and association simultaneously. We propose a retrospective multilevel model (rMLM) approach to analyze sibship data by using genotypic information as the dependent variable....
Autores principales: | Zhao, Yang, Yu, Hao, Zhu, Ying, Ter-Minassian, Monica, Peng, Zhihang, Shen, Hongbing, Diao, Nancy, Chen, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270036/ https://www.ncbi.nlm.nih.gov/pubmed/22312441 http://dx.doi.org/10.1371/journal.pone.0031134 |
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