Inhibition of cell cycle progression by dual phosphatidylinositol-3-kinase and mTOR blockade in cyclin D2 positive multiple myeloma bearing IgH translocations

Multiple myeloma (MM) is a clinically and genetically heterogenous cancer where tumour cells have dysregulated expression of a D-type cyclin, often in association with a recurrent IgH translocation. Patients whose tumour cells express cyclin D2, with the translocation t(4;14) or t(14;16), generally...

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Detalles Bibliográficos
Autores principales: Glassford, J, Kassen, D, Quinn, J, Stengel, C, Kallinikou, K, Khwaja, A, Yong, K L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270251/
https://www.ncbi.nlm.nih.gov/pubmed/22829234
http://dx.doi.org/10.1038/bcj.2011.44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270251/
https://www.ncbi.nlm.nih.gov/pubmed/22829234
http://dx.doi.org/10.1038/bcj.2011.44

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