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Drug-mediated inhibition of Fli-1 for the treatment of leukemia

The Ets transcription factor, Fli-1 is activated in murine erythroleukemia and overexpressed in various human malignancies including Ewing's sarcoma, induced by the oncogenic fusion protein EWS/Fli-1. Recent studies by our group and others have demonstrated that Fli-1 plays a key role in tumori...

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Detalles Bibliográficos
Autores principales:	Li, Y-J, Zhao, X, Vecchiarelli-Federico, L M, Li, Y, Datti, A, Cheng, Y, Ben-David, Y
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270256/ https://www.ncbi.nlm.nih.gov/pubmed/22829238 http://dx.doi.org/10.1038/bcj.2011.52

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