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Role of the promyelocytic leukaemia protein in cell death regulation

The promyelocytic leukaemia gene PML was originally identified at the t(15;17) translocation of acute promyelocytic leukaemia, which generates the oncogene PML-retinoic acid receptor α. PML epitomises a subnuclear structure called PML nuclear body. Current models propose that PML through its scaffol...

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Detalles Bibliográficos
Autores principales: Salomoni, P, Dvorkina, M, Michod, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270264/
https://www.ncbi.nlm.nih.gov/pubmed/22237204
http://dx.doi.org/10.1038/cddis.2011.122