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DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway
The DNA damage response (DDR) cascade and ROS (reactive oxygen species) signaling are both involved in the induction of cell death after DNA damage, but a mechanistic link between these two pathways has not been clearly elucidated. This study demonstrates that ROS induction after treatment of cells...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270268/ https://www.ncbi.nlm.nih.gov/pubmed/22237206 http://dx.doi.org/10.1038/cddis.2011.134 |