DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway

The DNA damage response (DDR) cascade and ROS (reactive oxygen species) signaling are both involved in the induction of cell death after DNA damage, but a mechanistic link between these two pathways has not been clearly elucidated. This study demonstrates that ROS induction after treatment of cells...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, M A, So, E-Y, Simons, A L, Spitz, D R, Ouchi, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270268/
https://www.ncbi.nlm.nih.gov/pubmed/22237206
http://dx.doi.org/10.1038/cddis.2011.134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270268/
https://www.ncbi.nlm.nih.gov/pubmed/22237206
http://dx.doi.org/10.1038/cddis.2011.134

Ejemplares similares