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Involvement of K(v)1.3 and p38 MAPK signaling in HIV-1 glycoprotein 120-induced microglia neurotoxicity

Inflammatory responses mediated by activated microglia play a pivotal role in the pathogenesis of human immunodeficiency virus type 1 (HIV-1)-associated neurocognitive disorders. Studies on identification of specific targets to control microglia activation and resultant neurotoxic activity are imper...

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Detalles Bibliográficos
Autores principales: Liu, J, Xu, C, Chen, L, Xu, P, Xiong, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270274/
https://www.ncbi.nlm.nih.gov/pubmed/22258405
http://dx.doi.org/10.1038/cddis.2011.140