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Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer

Changes in mitochondrial genome such as mutation, deletion and depletion are common in cancer and can determine advanced phenotype of cancer; however, detailed mechanisms have not been elucidated. We observed that loss of mitochondrial genome reversibly induced overexpression and activation of proto...

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Detalles Bibliográficos
Autores principales: Cook, C C, Kim, A, Terao, S, Gotoh, A, Higuchi, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270275/
https://www.ncbi.nlm.nih.gov/pubmed/22258408
http://dx.doi.org/10.1038/cddis.2011.141