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Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer
Changes in mitochondrial genome such as mutation, deletion and depletion are common in cancer and can determine advanced phenotype of cancer; however, detailed mechanisms have not been elucidated. We observed that loss of mitochondrial genome reversibly induced overexpression and activation of proto...
Autores principales: | Cook, C C, Kim, A, Terao, S, Gotoh, A, Higuchi, M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270275/ https://www.ncbi.nlm.nih.gov/pubmed/22258408 http://dx.doi.org/10.1038/cddis.2011.141 |
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