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Identification, subcellular localization, biochemical properties, and high-resolution crystal structure of Trypanosoma brucei UDP-glucose pyrophosphorylase

The protozoan parasite Trypanosoma brucei is the causative agent of the cattle disease Nagana and human African sleeping sickness. Glycoproteins play key roles in the parasite’s survival and infectivity, and the de novo biosyntheses of the sugar nucleotides UDP-galactose (UDP-Gal), UDP-N-acetylgluco...

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Detalles Bibliográficos
Autores principales: Mariño, Karina, Güther, Maria Lucia Sampaio, Wernimont, Amy K, Amani, Mernhaz, Hui, Raymond, Ferguson, Michael AJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270307/
https://www.ncbi.nlm.nih.gov/pubmed/20724435
http://dx.doi.org/10.1093/glycob/cwq115