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Sirolimus Enhances Cyclosporine A-Induced Cytotoxicity in Human Renal Glomerular Mesangial Cells

End Stage Renal Disease (ESRD) is an ever increasing problem worldwide. However the mechanisms underlying disease progression are not fully elucidated. This work addressed nephrotoxicity induced by the immunosuppressive agents' cyclosporine A (CsA) and sirolimus (SRL). Nephrotoxicity is the maj...

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Detalles Bibliográficos
Autores principales: O'Connell, Séin, Slattery, Craig, Ryan, Michael P., McMorrow, Tara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270447/
https://www.ncbi.nlm.nih.gov/pubmed/22315658
http://dx.doi.org/10.1155/2012/980910