Pegylated Arginine Deiminase Downregulates Colitis in Murine Models

Arginine deiminase (ADI), an arginine-metabolizing enzyme involved in cell signaling, is dysregulated in multiple inflammatory diseases and cancers. We hypothesized that pegylated ADI (ADI-PEG) provide protection against colitis. Methods. Dextran sodium sulfate colitis was induced in IL-10-deficient...

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Detalles Bibliográficos
Autores principales: Oz, Helieh S., Zhong, Jian, de Villiers, Willem J. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270451/
https://www.ncbi.nlm.nih.gov/pubmed/22315509
http://dx.doi.org/10.1155/2012/813892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270451/
https://www.ncbi.nlm.nih.gov/pubmed/22315509
http://dx.doi.org/10.1155/2012/813892

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