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Pegylated Arginine Deiminase Downregulates Colitis in Murine Models

Arginine deiminase (ADI), an arginine-metabolizing enzyme involved in cell signaling, is dysregulated in multiple inflammatory diseases and cancers. We hypothesized that pegylated ADI (ADI-PEG) provide protection against colitis. Methods. Dextran sodium sulfate colitis was induced in IL-10-deficient...

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Detalles Bibliográficos
Autores principales:	Oz, Helieh S., Zhong, Jian, de Villiers, Willem J. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270451/ https://www.ncbi.nlm.nih.gov/pubmed/22315509 http://dx.doi.org/10.1155/2012/813892

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