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PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways

The paraoxonase (PON) group of enzymes, composed of PON1, PON2, and PON3, play an important role in decreasing oxidative stress by degrading lipid peroxides. PON1 synthesis is upregulated by PPAR. Several pharmacological compounds (acting as antioxidants and, hence, atheroprotective) stimulate both...

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Detalles Bibliográficos
Autores principales: Camps, Jordi, García-Heredia, Anabel, Rull, Anna, Alonso-Villaverde, Carlos, Aragonès, Gerard, Beltrán-Debón, Raúl, Rodríguez-Gallego, Esther, Joven, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270466/
https://www.ncbi.nlm.nih.gov/pubmed/22315585
http://dx.doi.org/10.1155/2012/616371