Defective Cell Cycle Checkpoints as Targets for Anti-Cancer Therapies

Conventional chemotherapeutics target the proliferating fraction of cells in the patient’s body, which will include the tumor cells, but are also toxic to actively proliferating normal tissues. Cellular stresses, such as those imposed by chemotherapeutic drugs, induce cell cycle checkpoint arrest, a...

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Detalles Bibliográficos
Autores principales: Gabrielli, Brian, Brooks, Kelly, Pavey, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270485/
https://www.ncbi.nlm.nih.gov/pubmed/22347187
http://dx.doi.org/10.3389/fphar.2012.00009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270485/
https://www.ncbi.nlm.nih.gov/pubmed/22347187
http://dx.doi.org/10.3389/fphar.2012.00009

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