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Hydrolytic catalysis and structural stabilization in a designed metalloprotein
Metal ions are an important part of many natural proteins, providing structural, catalytic and electron transfer functions. Reproducing these functions in a designed protein is the ultimate challenge to our understanding of them. Here, we present an artificial metallohydrolase, which has been shown...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270697/ https://www.ncbi.nlm.nih.gov/pubmed/22270627 http://dx.doi.org/10.1038/nchem.1201 |