Cargando…
Hydrolytic catalysis and structural stabilization in a designed metalloprotein
Metal ions are an important part of many natural proteins, providing structural, catalytic and electron transfer functions. Reproducing these functions in a designed protein is the ultimate challenge to our understanding of them. Here, we present an artificial metallohydrolase, which has been shown...
Autores principales: | Zastrow, Melissa L., Peacock, Anna F. A., Stuckey, Jeanne A., Pecoraro, Vincent L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270697/ https://www.ncbi.nlm.nih.gov/pubmed/22270627 http://dx.doi.org/10.1038/nchem.1201 |
Ejemplares similares
-
Designing Hydrolytic Zinc Metalloenzymes
por: Zastrow, Melissa L., et al.
Publicado: (2014) -
Serial synchrotron and XFEL crystallography for studies of metalloprotein catalysis
por: Hough, Michael A., et al.
Publicado: (2021) -
Metalloprotein catalysis: structural and mechanistic insights into oxidoreductases from neutron protein crystallography
por: Schröder, Gabriela C., et al.
Publicado: (2021) -
Metals in Prebiotic
Catalysis: A Possible Evolutionary
Pathway for the Emergence of Metalloproteins
por: Aithal, Anuraag, et al.
Publicado: (2023) -
Metalloprotein Crystallography: More than a Structure
por: Bowman, Sarah E. J., et al.
Publicado: (2016)