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Integrating Flux Balance Analysis into Kinetic Models to Decipher the Dynamic Metabolism of Shewanella oneidensis MR-1

Shewanella oneidensis MR-1 sequentially utilizes lactate and its waste products (pyruvate and acetate) during batch culture. To decipher MR-1 metabolism, we integrated genome-scale flux balance analysis (FBA) into a multiple-substrate Monod model to perform the dynamic flux balance analysis (dFBA)....

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Detalles Bibliográficos
Autores principales: Feng, Xueyang, Xu, You, Chen, Yixin, Tang, Yinjie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271021/
https://www.ncbi.nlm.nih.gov/pubmed/22319437
http://dx.doi.org/10.1371/journal.pcbi.1002376